Peptomyc is focused on the development of a new generation of cell penetrating peptides (CPPs) targeting the Myc oncoprotein for cancer treatment. The company was founded in December 2014 and it is based on Dr. Soucek’s scientific research in Omomyc (the best direct Myc inhibitor known to date) over the last twenty years.
Abzu reveals early predictive response biomarker in first-ever clinically viable Myc oncogene.
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We supported a small team of researchers with experience in Oncology and Health Biology. Our work not only resulted in a successful clinical trial and patented models to predict right-candidate enrollment for phase II clinical trials, but also earned Peptomyc a publication in Nature Medicine.
Revealing early predictive response biomarkers for clinical trials.
We identified response biomarkers in metastatic patients treated with the first-in-class Myc oncogene inhibitor.
Until Peptomyc’s successful clinical trial with OMO-103, Myc was thought to be undruggable. The Myc oncogene is persistently expressed in Burkitt lymphoma as well as many cervix, colon, breast, lung, pancreatic, and stomach cancers, making it one of the most sought-after drug targets in cancer.
Peptomyc used the QLattice and Abzu’s expertise in patient stratification to reveal early predictive response-biomarkers to treatment with OMO-103 in metastatic patients. The analysis by the QLattice was conducted on a very small clinical trial of 22 patients.
This discovery made headlines.
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Contrary to the data-heavy demands of black-box AI, our technology thrives on minimal data. This efficiency not only accelerates the discovery process, but also reduces your barrier to entry to develop new, innovative drugs.