Reducing R&D risk with explainable AI

Our explainable models yielded a 44 percentage point improvement in catching toxic drugs in the drug development pipeline

We improved the hit-rate and reduced R&D risk for a top-10 pharmaceutical company

Our explainable models yielded a 44 percentage point improvement in catching toxic drugs in the drug development pipeline, reducing R&D risk and time.

Simple and explainable models yielded a 44 percentage point improvement in catching toxic drugs

Understanding what drives drug properties in conjunction with accurate drug activity predictions are clear advantages to improving drug candidate hit rate.

The customer: A top-10 pharmaceutical company

We supported a single Bioinformatician from a small bioinformatics department and Biologists and Chemists operating in a wet lab at an undisclosed top-10 pharmaceutical company.

Why Abzu?

Because traditional machine learning techniques don’t deliver enough actionable insights for scientists and researchers.

Technology + services

Abzu’s flexible services include our explainable AI, the QLattice®, and iterative lead generation and optimization.

The Abzoids

The Abzoids dedicated to this project were Casper Wilstrup, CEO, and Jaan Kasak, MSc in Theoretical and Mathematical Physics.

Revealing the “why” behind disease mechanisms and drug activity drastically reduces risk and timelines in drug development

Flexibility to suit your needs

Scientific understanding of drug properties of RNA therapeutics

Enhanced library design

Custom library of digital molecules for lead generation and optimization.
Abzu logo - xAI for RNATx

xAI modeling

Iterative lead optimization with our proprietary xAI and our experts in RNA therapeutics.
Potential deliverable: A report withg findings about RNATx efficacy, toxicity, etc

Digital report

Progress, recommendations, and actions to develop safe and efficacious therapeutics.

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Author

Elyse Sims

Elyse Sims

Elyse holds an EMBA from Georgia State University and wrangles Marketing and Communication for Abzu. She has 11+ years’ international marketing experience and prefers fast-paced startup environments. Elyse is an avid runner, CrossFit-er, gardener, reader, and swearer.

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